We observed the impact of broccoli sprout extract on alcohol-induced liver damage in mice. Over 14 days, various doses of broccoli extract were given to the mice, followed by alcohol exposure.
The results were promising, revealing that this extract significantly enhanced the liver's antioxidant capacity. Key protective proteins increased, while stress-related proteins decreased, suggesting that the extract helps shield the liver from the harmful effects of alcohol.
Overall, broccoli extract showed potential in supporting liver health in the context of alcohol consumption.
Read More
8
Broccoli aids liver disease treatment
Broccoli ( L. var. Planch) alleviates metabolic-associated fatty liver disease through regulating gut flora and lipid metabolism the FXR/LXR signaling pathway.
We explored how broccoli juice can assist in combating metabolic-associated fatty liver disease (MAFLD) using a study involving mice. Over 12 weeks, the mice on a high-fat diet showed promising improvements, including weight loss and reduced insulin resistance when given broccoli juice.
Broccoli helped lower harmful factors like blood glucose and cholesterol levels while enhancing beneficial traits such as antioxidant capacity. It also positively influenced gut flora.
However, while results were encouraging, further studies are necessary to fully understand the implications for human health.
Read More
7
Broccoli extracts reduce liver fat
Var by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity.
We evaluated how extracts from broccoli by-products might influence liver health, particularly concerning fat accumulation. Using liver cells exposed to fatty acids, we explored the impacts of broccoli leaves, stalks, and flower extracts.
While these extracts showed a dose-dependent reduction in cell viability, they managed to prevent harmful lipid accumulation without affecting cell function at non-lethal concentrations. Thus, broccoli extracts may offer a promising natural intervention to combat fat build-up in liver cells, particularly in the context of obesity-related conditions like non-alcoholic fatty liver disease.
Read More
Most Useful Reviews
9
Promotes glutathione production
231 people found this helpful
The main active ingredient, sulforaphane glucosinolate from broccoli seed extract, is excellent for liver disease as it promotes glutathione production in healthy cells, unlike typical antioxidants.
Read More
9
Weight loss aid
61 people found this helpful
This product has genuinely improved my health. Suffering from Non-Alcoholic Fatty Liver Disease, it helps regulate liver enzymes and contributes to weight loss while providing a boost in energy.
Read More
9
Sulforaphane benefits
28 people found this helpful
BroccoMax preserves myrosinase and aids in liver health as a potent inducer of phase 2 liver enzymes. This is vital for cellular protection and healthy cell replication. If my review is helpful, please let me know.
We aimed to see how broccoli extracts could combat liver damage from the toxic chemical DMBA in rats. Over 26 weeks, female rats received either water-based or methanol-based broccoli extracts after being exposed to DMBA. Our findings indicated that these broccoli extracts helped reduce oxidative stress and DNA damage in the liver.
While the extracts did have positive effects, they didn’t eliminate all signs of damage, suggesting that broccoli is a helpful dietary addition, but not a complete solution against environmental toxins.
Read More
9
Broccoli compound shows cancer-fighting potential
3,3'-Diindolylmethane Suppresses the Growth of Hepatocellular Carcinoma by Regulating Its Invasion, Migration, and ER Stress-Mediated Mitochondrial Apoptosis.
We investigated the potential of 3,3'-diindolylmethane (DIM), a compound found in broccoli and other cruciferous vegetables, in combating hepatocellular carcinoma (HCC). Through various assays, we observed that DIM markedly inhibited the growth, migration, and invasion of liver cancer cells.
Moreover, treatment with DIM activated specific pathways that led to cancer cell death, suggesting its promise as an anticancer agent for HCC. However, further studies are needed to fully understand its mechanisms and therapeutic applications.
Read More
9
Broccoli extract shows liver protection
Broccoli Sprout Extract Alleviates Alcohol-Induced Oxidative Stress and Endoplasmic Reticulum Stress in C57BL/6 Mice.
We observed the impact of broccoli sprout extract on alcohol-induced liver damage in mice. Over 14 days, various doses of broccoli extract were given to the mice, followed by alcohol exposure.
The results were promising, revealing that this extract significantly enhanced the liver's antioxidant capacity. Key protective proteins increased, while stress-related proteins decreased, suggesting that the extract helps shield the liver from the harmful effects of alcohol.
Overall, broccoli extract showed potential in supporting liver health in the context of alcohol consumption.
Read More
8
Broccoli aids liver disease treatment
Broccoli ( L. var. Planch) alleviates metabolic-associated fatty liver disease through regulating gut flora and lipid metabolism the FXR/LXR signaling pathway.
We explored how broccoli juice can assist in combating metabolic-associated fatty liver disease (MAFLD) using a study involving mice. Over 12 weeks, the mice on a high-fat diet showed promising improvements, including weight loss and reduced insulin resistance when given broccoli juice.
Broccoli helped lower harmful factors like blood glucose and cholesterol levels while enhancing beneficial traits such as antioxidant capacity. It also positively influenced gut flora.
However, while results were encouraging, further studies are necessary to fully understand the implications for human health.
Read More
8
Broccoli powder improves liver health
Maternal Broccoli Powder Intake Ameliorates Insulin Resistance and Inflammation via AMPK/mTOR Pathway in the Livers of High-Fructose-Fed Male Rat Offspring Exposed to Maternal Protein Restriction.
We examined how maternal intake of broccoli powder during lactation impacts liver health in offspring exposed to a high-fructose diet and maternal protein deficiency. Our research on pregnant rats showed that those consuming broccoli powder had sons with improved insulin sensitivity and reduced liver inflammation.
Specifically, offspring from low protein mothers who received broccoli powder maintained lower insulin levels and showed less macrophage infiltration in the liver. Overall, it appears that adding broccoli to a pregnant rat's diet can positively influence liver health in their male offspring later in life.
The main active ingredient, sulforaphane glucosinolate from broccoli seed extract, is excellent for liver disease as it promotes glutathione production in healthy cells, unlike typical antioxidants.
Read More
9
Weight loss aid
61 people found this helpful
This product has genuinely improved my health. Suffering from Non-Alcoholic Fatty Liver Disease, it helps regulate liver enzymes and contributes to weight loss while providing a boost in energy.
Read More
9
Sulforaphane benefits
28 people found this helpful
BroccoMax preserves myrosinase and aids in liver health as a potent inducer of phase 2 liver enzymes. This is vital for cellular protection and healthy cell replication. If my review is helpful, please let me know.
Read More
9
Liver recovery
28 people found this helpful
Due to a chronic illness, my liver was in distress from medication. Since I began taking BroccoMax, my liver function has dramatically improved. I no longer feel ill while taking my required medications.
Read More
9
Notable improvement
19 people found this helpful
My ALT and AST levels were high for a decade, but after taking BroccoMax for six months, my liver function tests showed significant improvement. I will continue taking it for life as it’s the first supplement that showed tangible results.
Liver disease encompasses a variety of conditions that affect the liver's ability to function effectively. The liver is a vital organ responsible for many important tasks, including metabolizing nutrients, detoxifying harmful substances, and producing bile for digestion. Common forms of liver disease include hepatitis, fatty liver disease, cirrhosis, and liver cancer. Each of these conditions can significantly impact liver function and overall health, leading to symptoms that range from fatigue and jaundice to more serious complications requiring urgent medical attention.
The causes of liver disease are diverse and can include chronic alcohol abuse, viral infections, autoimmune disorders, and metabolic conditions like obesity and diabetes. Early detection is key to managing liver disease effectively, often involving lifestyle changes, medications, and sometimes surgical interventions. Regular check-ups and liver function tests are recommended for individuals at higher risk, such as those with a family history of liver disease or those who lead certain lifestyle habits. Adopting a balanced diet and reducing alcohol intake can greatly aid in liver health and help prevent the onset of these conditions.
Broccoli is a nutrient-rich vegetable that belongs to the Brassica family, which includes other cruciferous vegetables like cauliflower, cabbage, and kale. This green plant is typically characterized by its thick stalk and tightly clustered flower heads, which are harvested for consumption. Broccoli is often celebrated for its impressive health benefits, as it's an excellent source of vitamins C and K, fiber, and various antioxidants. It's commonly enjoyed both raw in salads and cooked in a variety of dishes, including stir-fries, casseroles, and soups.
In addition to its nutritional value, broccoli is known for its versatility in cooking. It can be steamed, roasted, sautéed, or even grilled, making it easy to incorporate into different meals. Whether you’re looking to boost your vegetable intake or explore new flavors in your cooking, adding broccoli to your diet is a delicious way to enhance your overall health. Its mild, slightly peppery taste pairs well with an array of ingredients, from garlic and lemon to cheese and soy sauce, making it a favorite among chefs and home cooks alike.
Broccoli is often touted for its numerous health benefits, including its potential positive effects on liver health. This cruciferous vegetable is rich in antioxidants, particularly sulforaphane, which may help detoxify the liver and reduce inflammation—two important factors in managing liver disease. Studies suggest that regular consumption of broccoli and other cruciferous vegetables can bolster liver enzyme function and may protect against fatty liver disease by promoting the elimination of toxins from the body and enhancing overall liver function.
Additionally, broccoli contains high levels of vitamins C and K, folate, and fiber, all of which contribute to maintaining overall health. While incorporating broccoli into your diet may support liver health, it should be viewed as a complementary approach rather than a standalone treatment. If you or someone you know is dealing with liver disease, it's crucial to consult with a healthcare provider for a comprehensive treatment plan that includes dietary recommendations specific to individual health needs.
Based on user reviews, the time it takes to notice improvements in liver health while taking this supplement typically varies, but several users have reported significant results within a timeframe of around three to six months. For instance, one user noted their liver function tests showed significant improvement after taking BroccoMax for six months (Read Review), while another user, who had been diagnosed with fatty liver, stated they no longer fell under that classification after three years of consistent use (Read Review).
Other reviews also suggest that noticeable improvements can occur sooner, with some users feeling healthier after only a few months of usage (Read Review). Overall, many users emphasize the importance of consistent use over time to truly benefit from the liver-supporting properties of the supplement.
Recent research indicates that broccoli and its compounds, particularly sulforaphane, show promise in supporting liver health. Various studies reveal that dietary broccoli can improve insulin sensitivity and reduce inflammation linked to liver diseases like non-alcoholic fatty liver disease (NAFLD) and metabolic-associated fatty liver disease (MAFLD) in animal models. For instance, one study found that sulforaphane administered to participants with NAFLD significantly decreased blood sugar levels and enhanced insulin sensitivity, while also encouraging beneficial gut bacteria that play a role in reducing inflammation associated with liver problems [3]. Another study found that the intake of broccoli juice in mice helped reduce insulin resistance and lower blood glucose and cholesterol levels, suggesting a multifaceted approach to liver health through diet [1].
However, while these findings are encouraging, the majority of the studies conducted are based on animal models, and more extensive human trials are needed to draw definitive conclusions. Additionally, some studies also suggest that broccoli extracts can help mitigate liver damage from environmental toxins or alcohol exposure [5][16]. Overall, while there's a growing body of evidence supporting the potential benefits of broccoli for liver health, consumers should remain cautious and await further research before fully incorporating such supplements into their diet.
Based on user reviews, many individuals have reported marked improvements in their liver health after using BroccoMax, which contains the active ingredient sulforaphane glucosinolate derived from broccoli seed extract. Users have indicated that this supplement has promoted better liver function, with one user noting a significant reduction in liver-related symptoms after switching from other supplements (Read Review). Another user shared that they no longer fall under the classification of fatty liver after three years of consistent use (Read Review), while several others have experienced improvements in liver values during health check-ups after starting the supplement (Read Review, Read Review).
Users also report other benefits, such as increased energy and a general sense of well-being, alongside better liver health, suggesting that BroccoMax may support overall vitality (Read Review). However, it’s essential to remember that individual results can vary widely; what works well for one person may not hold the same efficacy for another. Consistency in use appears to be a common theme among those who have seen positive outcomes, hinting at the importance of regular supplementation for optimal liver support.
Based on user reviews, many individuals have reported positive experiences when combining BroccoMax with other supplements to address liver health. Notably, one user mentioned success in taking BroccoMax alongside DIM and calcium glucarate, which they found to enhance liver function through synergistic effects (Read Review). Additionally, another user indicated that taking BroccoMax contributed to improved skin and increased energy, suggesting that pairing it with other supplements can amplify the overall health benefits for liver function (Read Review).
Users generally emphasize the importance of using BroccoMax as a foundational supplement for liver health, with reports highlighting its unique ability to promote glutathione production and support phase 2 liver enzymes (Read Review). Combining BroccoMax with other health-minded supplements appears to provide additional support for users dealing with complex liver issues or other health concerns, as seen in cases involving chronic illnesses and hormonal imbalances.
Based on user reviews, many consumers have found significant benefits when using Broccoli supplements, particularly BroccoMax, for liver health. Users report improvements in liver function metrics such as ALT and AST levels after consistent use of the product. One review mentions that a daily intake of 30 mg of sulforaphane glucosinolate, which BroccoMax provides in each capsule, significantly enhances liver function (Read Review). Numerous individuals have observed tangible results, with several stating they plan to continue taking the supplement for life due to the notable improvements experienced (Read Review).
Users commonly highlight the importance of sulforaphane's role in detoxifying and protecting liver health, as well as its ability to support cellular protection and replication through inducing liver enzymes necessary for these processes (Read Review). Furthermore, individuals appreciate the ease of incorporation of the supplement into daily routines, often sharing positive health transformations relating to their liver functions after starting BroccoMax (Read Review). Overall, while specific dosage experiences may vary, a consistent intake of 30 mg is frequently mentioned as effective for enhancing liver health.
9
Notable improvement
19 people found this helpful
My ALT and AST levels were high for a decade, but after taking BroccoMax for six months, my liver function tests showed significant improvement. I will continue taking it for life as it’s the first supplement that showed tangible results.
7.5
Fatty liver improvement
21 people found this helpful
After being diagnosed with fatty liver for over 20 years, I’ve been taking this supplement for three years, and I’m no longer classified as having fatty liver. I attribute this improvement to my supplement use.
9
Normal liver values
17 people found this helpful
Although I can't confirm without check-ups, I feel my liver is healthier. I have a serious fatty liver condition, but after consistently taking this supplement, I’ve noticed improvements in my liver values.
9
Liver recovery
28 people found this helpful
Due to a chronic illness, my liver was in distress from medication. Since I began taking BroccoMax, my liver function has dramatically improved. I no longer feel ill while taking my required medications.
9
Effective for fatty liver
1 people found this helpful
I bought this for my husband who suffers from liver disease. It has significantly improved his liver function according to blood tests.
9
Improved liver values
2 people found this helpful
After taking this supplement, my liver values improved significantly. The quality and ingredients are excellent, making this an essential supplement for my liver health.
9
Boosts health immunity
1 people found this helpful
After using Jarrow Formulas' BroccoMax, I've experienced significant health improvements, including better energy and immune function, which is crucial for my liver health.
7.5
Improved estrogen metabolism
8 people found this helpful
Myrosinase activated sulforaphane is remarkable for addressing estrogen dominance syndrome. It has positively affected my condition and reduced harmful estrogen metabolites in my urine. The dosage is ideal, and I've combined it with DIM and calcium glucarate for better liver function.
7.5
Liver condition improvement
7 people found this helpful
This product has significantly benefited my husband's liver issues. After using sulphoraphane, he has more energy and improved skin. Although it initially upset my stomach, I found it generally beneficial for our liver health.
9
Promotes glutathione production
231 people found this helpful
The main active ingredient, sulforaphane glucosinolate from broccoli seed extract, is excellent for liver disease as it promotes glutathione production in healthy cells, unlike typical antioxidants.
9
Improves liver function
16 people found this helpful
Research from Tokai University indicated that a daily intake of 30 mg of sulforaphane glucosinolate significantly improves liver function. BroccoMax provides this dosage in one capsule.
9
Sulforaphane benefits
28 people found this helpful
BroccoMax preserves myrosinase and aids in liver health as a potent inducer of phase 2 liver enzymes. This is vital for cellular protection and healthy cell replication. If my review is helpful, please let me know.
8
Broccoli's sulforaphane shows promise
Improving insulin resistance by sulforaphane activating the and SCFAs-GPR-GLP1 signal axis.
We investigated the effects of sulforaphane, a compound found in broccoli, on liver disease and insulin resistance. Using a controlled trial, we administered broccoli seed tablets to participants with non-alcoholic fatty liver disease for 12 weeks. We observed that sulforaphane lowered blood sugar levels and improved insulin sensitivity. It also positively influenced gut bacteria, promoting beneficial types that helped reduce inflammation linked to liver issues. Overall, we found promising evidence that sulforaphane could be a valuable ally in managing liver health.
8
Broccoli aids liver disease treatment
Broccoli ( L. var. Planch) alleviates metabolic-associated fatty liver disease through regulating gut flora and lipid metabolism the FXR/LXR signaling pathway.
We explored how broccoli juice can assist in combating metabolic-associated fatty liver disease (MAFLD) using a study involving mice. Over 12 weeks, the mice on a high-fat diet showed promising improvements, including weight loss and reduced insulin resistance when given broccoli juice.
Broccoli helped lower harmful factors like blood glucose and cholesterol levels while enhancing beneficial traits such as antioxidant capacity. It also positively influenced gut flora.
However, while results were encouraging, further studies are necessary to fully understand the implications for human health.
9
Broccoli shows protective liver effects
Potential chemopreventive effects of Broccoli extract supplementation against 7, 12 dimethyl Benz(a)anthracene (DMBA) -induced toxicity in female rats.
We aimed to see how broccoli extracts could combat liver damage from the toxic chemical DMBA in rats. Over 26 weeks, female rats received either water-based or methanol-based broccoli extracts after being exposed to DMBA. Our findings indicated that these broccoli extracts helped reduce oxidative stress and DNA damage in the liver.
While the extracts did have positive effects, they didn’t eliminate all signs of damage, suggesting that broccoli is a helpful dietary addition, but not a complete solution against environmental toxins.
9
Broccoli extract shows liver protection
Broccoli Sprout Extract Alleviates Alcohol-Induced Oxidative Stress and Endoplasmic Reticulum Stress in C57BL/6 Mice.
We observed the impact of broccoli sprout extract on alcohol-induced liver damage in mice. Over 14 days, various doses of broccoli extract were given to the mice, followed by alcohol exposure.
The results were promising, revealing that this extract significantly enhanced the liver's antioxidant capacity. Key protective proteins increased, while stress-related proteins decreased, suggesting that the extract helps shield the liver from the harmful effects of alcohol.
Overall, broccoli extract showed potential in supporting liver health in the context of alcohol consumption.
References
Lu Y, Li X, Ma S, Ding M, Yang F, et al. Broccoli ( L. var. Planch) alleviates metabolic-associated fatty liver disease through regulating gut flora and lipid metabolism the FXR/LXR signaling pathway. Food Funct. 2025;16:1218. doi:10.1039/d4fo03731f
Karmacharya A, Kasai S, Mukai Y, Sato S. Maternal Broccoli Powder Intake Ameliorates Insulin Resistance and Inflammation via AMPK/mTOR Pathway in the Livers of High-Fructose-Fed Male Rat Offspring Exposed to Maternal Protein Restriction. Mol Nutr Food Res. 2024;68:e2400472. doi:10.1002/mnfr.202400472
Tian S, Lei Y, Zhao F, Che J, Wu Y, et al. Improving insulin resistance by sulforaphane activating the and SCFAs-GPR-GLP1 signal axis. Food Funct. 2024;15:8644. doi:10.1039/d4fo01059k
Yang Y, Eguchi A, Mori C, Hashimoto K. Dietary sulforaphane glucosinolate mitigates depression-like behaviors in mice with hepatic ischemia/reperfusion injury: A role of the gut-liver-brain axis. J Psychiatr Res. 2024;176:129. doi:10.1016/j.jpsychires.2024.06.005
Allam AM, AbuBakr HO, Yassin AM, Abdel-Razek AS, Khattab MS, et al. Potential chemopreventive effects of Broccoli extract supplementation against 7, 12 dimethyl Benz(a)anthracene (DMBA) -induced toxicity in female rats. Sci Rep. 2023;13:17234. doi:10.1038/s41598-023-43629-2
Castelão-Baptista JP, Valente SA, Canário S, Oppolzer D, Barros A, et al. Var by-Products Prevent Lipid Accumulation and Cell Death in a Liver Cell Model of Lipid Toxicity. Nutrients. 2023;15. doi:10.3390/nu15040924
Zhao L, Jin L, Petrick JL, Zeng H, Wang F, et al. Specific botanical groups of fruit and vegetable consumption and liver cancer and chronic liver disease mortality: a prospective cohort study. Am J Clin Nutr. 2023;117:278. doi:10.1016/j.ajcnut.2022.12.004
Raza AA, Mushtaq R, Khwaja S, Akram A, Karim A, et al. Antioxidant associated chemoprophylaxis effect of natural spice and green vegetable on hepatotoxicity. Braz J Biol. 2023;84:e266940. doi:10.1590/1519-6984.266940
Mansour SZ, Moustafa EM, Moawed FSM. Modulation of endoplasmic reticulum stress via sulforaphane-mediated AMPK upregulation against nonalcoholic fatty liver disease in rats. Cell Stress Chaperones. 2022;27:499. doi:10.1007/s12192-022-01286-w
Zandani G, Anavi-Cohen S, Tsybina-Shimshilashvili N, Sela N, Nyska A, et al. Broccoli Florets Supplementation Improves Insulin Sensitivity and Alters Gut Microbiome Population-A Steatosis Mice Model Induced by High-Fat Diet. Front Nutr. 2021;8:680241. doi:10.3389/fnut.2021.680241
Munakarmi S, Shrestha J, Shin HB, Lee GH, Jeong YJ. 3,3'-Diindolylmethane Suppresses the Growth of Hepatocellular Carcinoma by Regulating Its Invasion, Migration, and ER Stress-Mediated Mitochondrial Apoptosis. Cells. 2021;10. doi:10.3390/cells10051178
Du K, Fan Y, Li D. Sulforaphane ameliorates lipid profile in rodents: an updated systematic review and meta-analysis. Sci Rep. 2021;11:7804. doi:10.1038/s41598-021-87367-9
Eve AA, Liu X, Wang Y, Miller MJ, Jeffery EH, et al. Biomarkers of Broccoli Consumption: Implications for Glutathione Metabolism and Liver Health. Nutrients. 2020;12. doi:10.3390/nu12092514
Xu L, Nagata N, Ota T. Impact of Glucoraphanin-Mediated Activation of Nrf2 on Non-Alcoholic Fatty Liver Disease with a Focus on Mitochondrial Dysfunction. Int J Mol Sci. 2019;20. doi:10.3390/ijms20235920
Lee C, Yang S, Lee BS, Jeong SY, Kim KM, et al. Hepatic protective effects of sulforaphane through the modulation of inflammatory pathways. J Asian Nat Prod Res. 2020;22:386. doi:10.1080/10286020.2019.1581174
Lei P, Zhao W, Pang B, Yang X, Li BL, et al. Broccoli Sprout Extract Alleviates Alcohol-Induced Oxidative Stress and Endoplasmic Reticulum Stress in C57BL/6 Mice. J Agric Food Chem. 2018;66:5574. doi:10.1021/acs.jafc.8b01653